L-Arginine/Nitric Oxide Pathway Is Altered in Colorectal Cancer and Can Be Modulated by Novel Derivatives from Oxicam Class of Non-Steroidal Anti-Inflammatory Drugs

SIMPLE SUMMARY: Nitric oxide and arginine metabolism in colorectal cancer (CRC) holds potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams, a class of non-steroidal anti-inflammatory drugs with documented chemopreventive and antineoplastic activity. The aim of...

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Pubblicato in:Cancers (Basel)
Autori principali: Krzystek-Korpacka, Małgorzata, Szczęśniak-Sięga, Berenika, Szczuka, Izabela, Fortuna, Paulina, Zawadzki, Marek, Kubiak, Agnieszka, Mierzchała-Pasierb, Magdalena, Fleszar, Mariusz G., Lewandowski, Łukasz, Serek, Paweł, Jamrozik, Natalia, Neubauer, Katarzyna, Wiśniewski, Jerzy, Kempiński, Radosław, Witkiewicz, Wojciech, Bednarz-Misa, Iwona
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564351/
https://ncbi.nlm.nih.gov/pubmed/32932854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092594
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