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Pharmaco‐genetic inhibition of pyramidal neurons retards hippocampal kindling‐induced epileptogenesis

AIMS: Pharmaco‐genetics emerges as a new promising approach for epileptic seizures. Whether it can modulate epileptogenesis is still unknown. METHODS: Here, parvalbumin neurons and pyramidal neurons of the seizure focus were transfected with engineered excitatory Gq‐coupled human muscarinic receptor...

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Publicat a:CNS Neurosci Ther
Autors principals: Chen, Li‐Ying, Liang, Jiao, Fei, Fan, Ruan, Ye‐Ping, Cheng, He‐Ming, Wang, Yi, Chen, Zhong, Xu, Ceng‐Lin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564188/
https://ncbi.nlm.nih.gov/pubmed/32596972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13434
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