Effect of CYP3A4*22 and PPAR-α Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention

This study aims to determine whether genetic variants that influence CYP3A4 expression are associated with platelet reactivity in clopidogrel-treated patients undergoing elective percutaneous coronary intervention (PCI), and to evaluate the influence of statin/fibrate co-medication on these associat...

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Publicat a:Genes (Basel)
Autors principals: Bergmeijer, Thomas O., Yasmina, Alfi, Vos, Gerrit J. A., Janssen, Paul W. A., Hackeng, Christian M., Kelder, Johannes C., Verma, Shefali S., Ritchie, Marylyn D., Gong, Li, Klein, Teri E., de Boer, Anthonius, Klungel, Olaf H., ten Berg, Jurriën M., Deneer, Vera H. M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564055/
https://ncbi.nlm.nih.gov/pubmed/32932966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11091068
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