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Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells

DNA damage response inhibitors (DDRi) may selectively enhance the inactivation of tumor cells in combination with ionizing radiation (IR). The induction of senescence may be the key mechanism of tumor cell inactivation in this combinatorial treatment. In the current study the effect of combined IR w...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Dobler, Clara, Jost, Tina, Hecht, Markus, Fietkau, Rainer, Distel, Luitpold
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563880/
https://ncbi.nlm.nih.gov/pubmed/32883016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092012
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