Increased Elastin Degradation in Pseudoxanthoma Elasticum Is Associated with Peripheral Arterial Disease Independent of Calcification

Pseudoxanthoma elasticum (PXE) results in extensive fragmentation and calcification of elastin fibers in the peripheral arteries, which results in peripheral arterial disease (PAD). Current research focuses on the role of calcifications in the pathogenesis of PXE. Elastin degradation and calcificati...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Bartstra, Jonas W., Spiering, Wilko, van den Ouweland, Jody M. W., Mali, Willem P. T. M., Janssen, Rob, de Jong, Pim A.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563692/
https://ncbi.nlm.nih.gov/pubmed/32859086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9092771
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