Increased Elastin Degradation in Pseudoxanthoma Elasticum Is Associated with Peripheral Arterial Disease Independent of Calcification

Pseudoxanthoma elasticum (PXE) results in extensive fragmentation and calcification of elastin fibers in the peripheral arteries, which results in peripheral arterial disease (PAD). Current research focuses on the role of calcifications in the pathogenesis of PXE. Elastin degradation and calcificati...

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Udgivet i:J Clin Med
Main Authors: Bartstra, Jonas W., Spiering, Wilko, van den Ouweland, Jody M. W., Mali, Willem P. T. M., Janssen, Rob, de Jong, Pim A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563692/
https://ncbi.nlm.nih.gov/pubmed/32859086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9092771
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