Effect of CYP3A5 on the Once-Daily Tacrolimus Conversion in Stable Liver Transplant Patients

Cytochrome P450 (CYP) 3A5 polymorphism influences tacrolimus metabolism, but its effect on the drug pharmacokinetics in liver transplant recipients switched to once-daily extended-release formulation remains unknown. The aim of this study is to analyze the effect of CYP3A5 polymorphism on liver func...

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Publicado no:J Clin Med
Main Authors: Kim, Jong Man, Ryu, Je Ho, Lee, Kwang-Woong, Hong, Suk Kyun, Yang, Kwangho, Choi, Gyu-Seong, Kim, Young-Ae, Lee, Ju-Yeun, Yi, Nam-Joon, Kwon, Choon Hyuck David, Chu, Chong Woo, Suh, Kyung-Suk, Joh, Jae-Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563461/
https://ncbi.nlm.nih.gov/pubmed/32911703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9092897
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