Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis

We report whole-genome and intra-host variability of SARS-Cov-2 assessed by next generation sequencing (NGS) in upper (URT) and lower respiratory tract (LRT) from COVID-19 patients. The aim was to identify possible tissue-specific patterns and signatures of variant selection for each respiratory com...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Rueca, Martina, Bartolini, Barbara, Gruber, Cesare Ernesto Maria, Piralla, Antonio, Baldanti, Fausto, Giombini, Emanuela, Messina, Francesco, Marchioni, Luisa, Ippolito, Giuseppe, Di Caro, Antonino, Capobianchi, Maria Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563410/
https://ncbi.nlm.nih.gov/pubmed/32858978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8091302
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