Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine

The immune response to live-attenuated Francisella tularensis vaccine and its host evasion mechanisms are incompletely understood. Using RNA-Seq and LC–MS on samples collected pre-vaccination and at days 1, 2, 7, and 14 post-vaccination, we identified differentially expressed genes in PBMCs, metabol...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Goll, Johannes B., Li, Shuzhao, Edwards, James L., Bosinger, Steven E., Jensen, Travis L., Wang, Yating, Hooper, William F., Gelber, Casey E., Sanders, Katherine L., Anderson, Evan J., Rouphael, Nadine, Natrajan, Muktha S., Johnson, Robert A., Sanz, Patrick, Hoft, Daniel, Mulligan, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563297/
https://ncbi.nlm.nih.gov/pubmed/32722194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030412
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