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Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma

SIMPLE SUMMARY: Acquired drug resistance remains a challenge in the management of cancer patients. Strategies to overcome drug resistance and enhance the response include the combination therapy with agents that target known resistance mechanisms. Inflammasomes are mediators of inflammation. We prev...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Zhai, Zili, Samson, Jenny Mae, Yamauchi, Takeshi, Vaddi, Prasanna K., Matsumoto, Yuko, Dinarello, Charles A., Ravindran Menon, Dinoop, Fujita, Mayumi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563249/
https://ncbi.nlm.nih.gov/pubmed/32899791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092518
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