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Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer

The CXCL12-CXCR4 axis plays a vital role in many steps of breast cancer metastasis, but the molecular mechanisms have not been fully elucidated. We previously reported that activation of CXCR4 by CXCL12 promotes the nuclear localization of LASP1 (LIM and SH3 protein 1). The nuclear LASP1 then intera...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Subramaniyan, Boopathi, Sridharan, Sangita, M. Howard, Cory, M.C. Tilley, Augustus, Basuroy, Tupa, de la Serna, Ivana, Butt, Elke, Raman, Dayanidhi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563118/
https://ncbi.nlm.nih.gov/pubmed/32825729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092372
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