Venetoclax in association with decitabine as effective bridge to transplant in a case of relapsed early T‐cell lymphoblastic leukemia

A case of an early‐relapsed high‐risk T‐ALL with high BCL‐2 expression on leukemic blasts was successfully treated with decitabine and venetoclax, achieving a CR. We suggest decitabine and venetoclax should be synergistic in BCL2‐positive ALL.

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Détails bibliographiques
Publié dans:Clin Case Rep
Auteurs principaux: Zappone, Elisabetta, Cencini, Emanuele, Defina, Marzia, Sicuranza, Anna, Gozzetti, Alessandro, Ciofini, Sara, Raspadori, Donatella, Mecacci, Bianca, Bocchia, Monica
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Case Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562845/
https://ncbi.nlm.nih.gov/pubmed/33088538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.3041
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