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Effects of CYP2B6 polymorphisms on plasma nevirapine concentrations: a systematic review and meta-analysis

Cytochrome P450 (CYP) is involved in the metabolism of nevirapine (NVP); especially, CYP2B6 has been known to be one of the main enzymes involved in NVP metabolism. The objective of this study was to investigate the effects of CYP2B6 variants on plasma concentrations of NVP by a systematic review an...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yoon, Ha Young, Cho, Young Ah, Yee, Jeong, Gwak, Hye Sun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562737/
https://ncbi.nlm.nih.gov/pubmed/33060725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74506-x
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