A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists

Gleason score 7 prostate cancer with a higher proportion of pattern 4 (G4) has been linked to genomic heterogeneity and poorer patient outcome. The current assessment of G4 proportion uses estimation by a pathologist, with a higher proportion of G4 more likely to trigger additional imaging and treat...

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Publicado no:Sci Rep
Main Authors: Carmona Echeverria, Lina Maria, Haider, Aiman, Freeman, Alex, Stopka-Farooqui, Urszula, Rosenfeld, Avi, Simpson, Benjamin S., Hu, Yipeng, Hawkes, David, Pye, Hayley, Heavey, Susan, Stavrinides, Vasilis, Norris, Joseph M., Bosaily, Ahmed El-Shater, Cardona Barrena, Cristina, Bott, Simon, Brown, Louise, Burns-Cox, Nick, Dudderidge, Tim, Henderson, Alastair, Hindley, Richard, Kaplan, Richard, Kirkham, Alex, Oldroyd, Robert, Ghei, Maneesh, Persad, Raj, Punwani, Shonit, Rosario, Derek, Shergill, Iqbal, Winkler, Mathias, Ahmed, Hashim U., Emberton, Mark, Whitaker, Hayley C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561724/
https://ncbi.nlm.nih.gov/pubmed/33057024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73524-z
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