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Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome
Protein aggregates are the pathogenic hallmarks of many different neurodegenerative diseases and include the accumulation of α-synuclein, the main component of Lewy bodies found in Parkinson's disease. Aggresomes are closely-related, cellular accumulations of misfolded proteins. They develop in...
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| Publicado no: | Biol Open |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7561473/ https://ncbi.nlm.nih.gov/pubmed/32878882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.054338 |
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