Combinational PRR Agonists in Liposomal Adjuvant Enhances Immunogenicity and Protective Efficacy in a Tuberculosis Subunit Vaccine

Bacillus Calmette-Guerin (BCG) is the only licensed vaccine to prevent children from tuberculosis (TB), whereas it cannot provide effective protection for adults. Our previous work showed a novel vaccine candidate, liposomal adjuvant DMT emulsified with a multistage antigen CMFO, could protect mice...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Hao, Ling, Wu, Yaqi, Zhang, Yandi, Zhou, Zijie, Lei, Qing, Ullah, Nadeem, Banga Ndzouboukou, Jo-Lewis, Lin, Xiaosong, Fan, Xionglin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561437/
https://ncbi.nlm.nih.gov/pubmed/33117374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.575504
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