Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental Bronchopulmonary Dysplasia

Rationale: Antenatal inflammation with placental dysfunction is strongly associated with high bronchopulmonary dysplasia (BPD) risk in preterm infants. Whether antenatal or postnatal HIF (hypoxia-inducible factor) augmentation can preserve lung structure and function and prevent pulmonary hypertensi...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Hirsch, Kellen, Taglauer, Elizabeth, Seedorf, Gregory, Callahan, Carly, Mandell, Erica, White, Carl W., Kourembanas, Stella, Abman, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560790/
https://ncbi.nlm.nih.gov/pubmed/32551816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202003-0601OC
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