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Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi

Mitoribosomes are specialized protein synthesis machineries in mitochondria. However, how mRNA binds to its dedicated channel, and tRNA moves as the mitoribosomal subunit rotate with respect to each other is not understood. We report models of the translating fungal mitoribosome with mRNA, tRNA and...

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Vydáno v:Nat Commun
Hlavní autoři: Itoh, Yuzuru, Naschberger, Andreas, Mortezaei, Narges, Herrmann, Johannes M., Amunts, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560712/
https://ncbi.nlm.nih.gov/pubmed/33056988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18830-w
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