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A genotyping method combining primer competition PCR with HRM analysis to identify point mutations in Duchenne animal models

Dystrophin-null sapje zebrafish is an excellent model for better understanding the pathological mechanisms underlying Duchenne muscular dystrophy, and it has recently arisen as a powerful tool for high-throughput screening of therapeutic candidates for this disease. While dystrophic phenotype in sap...

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Publicado en:Sci Rep
Autores principales: Lasa-Fernandez, Haizpea, Mosqueira-Martín, Laura, Alzualde, Ainhoa, Lasa-Elgarresta, Jaione, Vallejo-Illarramendi, Ainara
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560699/
https://ncbi.nlm.nih.gov/pubmed/33057138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74173-y
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