An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics

Most patients with multiple myeloma (MM) die from progressive disease after relapse. To advance our understanding of MM evolution mechanisms, we performed whole-genome sequencing of 80 IGH-translocated tumour-normal newly diagnosed pairs and 24 matched relapsed tumours from the Myeloma XI trial. We...

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Foilsithe in:Blood Cancer J
Main Authors: Hoang, Phuc H., Cornish, Alex J., Sherborne, Amy L., Chubb, Daniel, Kimber, Scott, Jackson, Graham, Morgan, Gareth J., Cook, Gordon, Kinnersley, Ben, Kaiser, Martin, Houlston, Richard S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560599/
https://ncbi.nlm.nih.gov/pubmed/33057009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00367-2
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