Population Pharmacokinetics of Continuous-Infusion Meropenem in Febrile Neutropenic Patients with Hematologic Malignancies: Dosing Strategies for Optimizing Empirical Treatment against Enterobacterales and P. aeruginosa

A population pharmacokinetic analysis of continuous infusion (CI) meropenem was conducted in a prospective cohort of febrile neutropenic (FN) patients with hematologic malignancies. A non-parametric approach with Pmetrics was used for pharmacokinetic analysis and covariate evaluation. Monte Carlo si...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Cojutti, Pier Giorgio, Candoni, Anna, Lazzarotto, Davide, Filì, Carla, Zannier, Maria, Fanin, Renato, Pea, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560225/
https://ncbi.nlm.nih.gov/pubmed/32825109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090785
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