Association between Polygenic Risk Score and One-Year Outcomes Following As-Needed Aflibercept Therapy for Exudative Age-Related Macular Degeneration

We investigated whether polygenic risk score (PRS) was associated with one-year outcome of as-needed aflibercept therapy for exudative age-related macular degeneration (AMD), including AMD (n = 129) and polypoidal choroidal vasculopathy (n = 132). A total of 261 patients were treated with as-needed...

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Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Shijo, Taiyo, Sakurada, Yoichi, Yoneyama, Seigo, Kikushima, Wataru, Sugiyama, Atsushi, Matsubara, Mio, Fukuda, Yoshiko, Mabuchi, Fumihiko, Kashiwagi, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559528/
https://ncbi.nlm.nih.gov/pubmed/32962278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090257
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