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Bioinformatic gene analysis for potential therapeutic targets of Huntington’s disease in pre-symptomatic and symptomatic stage

BACKGROUND: Huntington’s disease (HD) is a neurodegenerative disorder characterized by psychiatric symptoms, serious motor and cognitive deficits. Certain pathological changes can already be observed in pre-symptomatic HD (pre-HD) patients; however, the underlying molecular pathogenesis is still unc...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Xiang, Chunchen, Cong, Shengri, Liang, Bin, Cong, Shuyan
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559361/
https://ncbi.nlm.nih.gov/pubmed/33054835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02549-9
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