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Screening of Bacterial Quorum Sensing Inhibitors in a Vibrio fischeri LuxR-Based Synthetic Fluorescent E. coli Biosensor

A library of 23 pure compounds of varying structural and chemical characteristics was screened for their quorum sensing (QS) inhibition activity using a synthetic fluorescent Escherichia coli biosensor that incorporates a modified version of lux regulon of Vibrio fischeri. Four such compounds exhibi...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Qin, Xiaofei, Vila-Sanjurjo, Celina, Singh, Ratna, Philipp, Bodo, Goycoolea, Francisco M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559085/
https://ncbi.nlm.nih.gov/pubmed/32971993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090263
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