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Impact of Sampling Period on Population Pharmacokinetic Analysis of Antibiotics: Why do You Take Blood Samples Following the Fourth Dose?

To date, many population pharmacokinetic models of antibiotics have been developed using blood sampling data after the fourth or fifth dose, which represents steady-state levels. However, if a model developed using blood sampled after the first dose is equivalent to that using blood sampled after th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Kim, So Won, Kim, Dong Jin, Zang, Dae Young, Lee, Dong-Hwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558941/
https://ncbi.nlm.nih.gov/pubmed/32947890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090249
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