PEGylation of Polyethylenimine Lowers Acute Toxicity while Retaining Anti-Biofilm and β-Lactam Potentiation Properties against Antibiotic-Resistant Pathogens

[Image: see text] Bacterial biofilms, often impenetrable to antibiotic medications, are a leading cause of poor wound healing. The prognosis is worse for wounds with biofilms of antimicrobial-resistant (AMR) bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant...

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Pubblicato in:ACS Omega
Autori principali: Lam, Anh K., Moen, Erika L., Pusavat, Jennifer, Wouters, Cassandra L., Panlilio, Hannah, Ferrell, Maya J., Houck, Matthew B., Glatzhofer, Daniel T., Rice, Charles V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557992/
https://ncbi.nlm.nih.gov/pubmed/33073153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04111
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