Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic presents an urgent need for an effective vaccine. Molecular characterization of SARS-CoV-2 is critical to the development of effective vaccine and therapeutic strategies. In the present study, we show that the fusion o...

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Detalhes bibliográficos
Publicado no:Membranes (Basel)
Main Authors: Azad, Taha, Singaravelu, Ragunath, Crupi, Mathieu J.F., Jamieson, Taylor, Dave, Jaahnavi, Brown, Emily E.F., Rezaei, Reza, Taha, Zaid, Boulton, Stephen, Martin, Nikolas T., Surendran, Abera, Poutou, Joanna, Ghahremani, Mina, Nouri, Kazem, Whelan, Jack T., Duong, Jessie, Tucker, Sarah, Diallo, Jean-Simon, Bell, John C., Ilkow, Carolina S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557813/
https://ncbi.nlm.nih.gov/pubmed/32872641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes10090215
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