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The role of hypoxia-induced modulation of alveolar epithelial Na(+)- transport in hypoxemia at high altitude

Reabsorption of excess alveolar fluid is driven by vectorial Na(+)-transport across alveolar epithelium, which protects from alveolar flooding and facilitates gas exchange. Hypoxia inhibits Na(+)-reabsorption in cultured cells and in-vivo by decreasing activity of epithelial Na(+)-channels (ENaC), w...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Baloglu, Emel, Nonnenmacher, Gabriel, Seleninova, Anna, Berg, Lena, Velineni, Kalpana, Ermis-Kaya, Ezgi, Mairbäurl, Heimo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557693/
https://ncbi.nlm.nih.gov/pubmed/33110497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020936662
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