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Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
AIMS: Endothelin-1 (ET-1) is a potent vasoconstrictor peptide linked to vascular diseases through a common intronic gene enhancer [(rs9349379-G allele), chromosome 6 (PHACTR1/EDN1)]. We performed a multimodality investigation into the role of ET-1 and this gene variant in the pathogenesis of coronar...
Shranjeno v:
| izdano v: | Eur Heart J |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7557475/ https://ncbi.nlm.nih.gov/pubmed/31972008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz915 |
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