Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice

Hereditary hemochromatosis (HH), an iron-overload disease, is a prevalent genetic disorder. As excess iron causes a multitude of metabolic disturbances, we postulated that iron overload in HH disrupts colonic homeostasis and colon–microbiome interaction and exacerbates the development and progressio...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Sivaprakasam, Sathish, Ristic, Bojana, Mudaliar, Nithya, Hamood, Abdul N., Colmer-Hamood, Jane, Wachtel, Mitchell S., Nevels, Anna G., Kottapalli, Kameswara R., Ganapathy, Vadivel
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557149/
https://ncbi.nlm.nih.gov/pubmed/32955078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200392
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