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X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Toxoplasmosis is a parasitic disease caused by infection with Toxoplasma gondii that currently has few therapeutic options. The M1 aminopeptidase enzymes have been shown to be attractive targets for anti-parasitic agents and/or vaccine candidates, suggesting potential to re-purpose inhibitors betwee...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Marijanovic, Emilia M., Weronika Swiderska, Karolina, Andersen, James, Aschenbrenner, Jasmin C., Webb, Chaille T., Drag, Marcin, Drinkwater, Nyssa, McGowan, Sheena
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557147/
https://ncbi.nlm.nih.gov/pubmed/32926129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200569
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