Population genetic and biophysical evidences reveal that purifying selection shapes the genetic landscape of Plasmodium falciparum RH ligands in Chhattisgarh and West Bengal, India

BACKGROUND: Reticulocyte binding protein-like homologs (RHs) are currently being evaluated as anti-erythrocytic stage vaccine targets against Plasmodium falciparum malaria. Present study explores the possible evolutionary drivers shaping the genetic organization of Pfrhs in Indian parasite populatio...

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Vydáno v:Malar J
Hlavní autoři: Ghoshal, Sharmistha, Chowdhury, Pramita, Ray, Sanhita, Mitra, Mitashree, Kanjilal, Sumana Datta, Sen, Srikanta, Dasgupta, Anjan Kr., Sengupta, Sanghamitra
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557104/
https://ncbi.nlm.nih.gov/pubmed/33054833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03433-z
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