Poly(POG)n loaded with recombinant human bone morphogenetic protein-2 accelerates new bone formation in a critical-sized bone defect mouse model

BACKGROUND: Delivery of bone morphogenetic protein-2 (BMP-2) via animal-derived absorbable collagen materials is used for the treatment of large bone defects. However, the administration of bovine proteins to humans is associated with the risk of zoonotic complications. We therefore examined the eff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Orthop Surg Res
Prif Awduron: Tazawa, Ryo, Uchida, Kentaro, Minehara, Hiroaki, Matsuura, Terumasa, Kawamura, Tadashi, Sekiguchi, Hiroyuki, Muneshige, Kyoko, Inoue, Sho, Inoue, Gen, Takaso, Masashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557057/
https://ncbi.nlm.nih.gov/pubmed/33054796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-01977-z
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