Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells

Differentiation status of tumors is correlated with metastatic potential and malignancy. FOXA1 (forkhead box A1) is a transcription factor known to regulate differentiation in certain tissues. Here, we investigate FOXA1 function in human colorectal cancer (CRC). We found that FOXA1 is robustly expre...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Lazar, Sarah B., Pongor, Lorinc, Li, Xiao Ling, Grammatikakis, Ioannis, Muys, Bruna R., Dangelmaier, Emily A., Redon, Christophe E., Jang, Sang-Min, Walker, Robert L., Tang, Wei, Ambs, Stefan, Harris, Curtis C., Meltzer, Paul S., Aladjem, Mirit I., Lal, Ashish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556848/
https://ncbi.nlm.nih.gov/pubmed/32839292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00224-20
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