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A comparative study of tolerability and effects on immunoglobulin levels and CD19 cell counts with ocrelizumab vs low dose of rituximab in multiple sclerosis

BACKGROUND: Rituximab (RTX) and ocrelizumab (OCR) are two anti-CD20 biologics used in MS; however, comparisons on safety and efficacy are rare. OBJECTIVE: To compare treatment outcomes over the first year with RTX and OCR. METHODS: Retrospective cohort study comprising MS patients initiating RTX at...

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Detalhes bibliográficos
Publicado no:Mult Scler J Exp Transl Clin
Main Authors: Evertsson, Björn, Hoyt, Tammy, Christensen, Angel, Nimer, Faiez AL, Foley, John, Piehl, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556182/
https://ncbi.nlm.nih.gov/pubmed/33110619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2055217320964505
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