Ivabradine-Stimulated Microvesicle Release Induces Cardiac Protection against Acute Myocardial Infarction

Ivabradine can reduce heart rate through inhibition of the current I(f) by still unexplored mechanisms. In a porcine model of ischemia reperfusion (IR), we found that treatment with 0.3 mg/kg Ivabradine increased plasma release of microvesicles (MVs) over Placebo, as detected by flow cytometry of pl...

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Pubblicato in:Int J Mol Sci
Autori principali: Ramirez-Carracedo, Rafael, Tesoro, Laura, Hernandez, Ignacio, Diez-Mata, Javier, Botana, Laura, Saura, Marta, Sanmartin, Marcelo, Zamorano, Jose Luis, Zaragoza, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555962/
https://ncbi.nlm.nih.gov/pubmed/32911752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186566
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