Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region

The administration of immune checkpoint inhibitors (ICIs) often leads to immune-related adverse events. However, their effect on auditory function is largely unexplored. Thorough preclinical studies have not been published yet, only sporadic cases and pharmacovigilance reports suggest their signific...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Szepesy, Judit, Miklós, Gabriella, Farkas, János, Kucsera, Dániel, Giricz, Zoltán, Gáborján, Anita, Polony, Gábor, Szirmai, Ágnes, Tamás, László, Köles, László, Varga, Zoltán V., Zelles, Tibor
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555949/
https://ncbi.nlm.nih.gov/pubmed/32933159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186701
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