Colon Transcriptomics Reveals Sex-Dependent Metabolic Signatures in Response to 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Treatment in C57BL/6N Mice

Diets high in red meats, particularly meats cooked at high temperature, increase the risk of colon cancer due to a production of heterocyclic aromatic amines (HAAs). Of the identified HAAs, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most mass abundant colon carcinogen in charred m...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Pan, Jeong Hoon, Cicalo, Cara, Le, Brandy, Jeon, Suwon, Kim, Sangyub, Hwang, Kyung A., Kong, Byungwhi, Lee, Jin Hyup, Kim, Jae Kyeom
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555907/
https://ncbi.nlm.nih.gov/pubmed/32927802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186620
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