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Infliximab concentrations in two non-switching cohorts of patients with inflammatory bowel disease: originator vs. biosimilar

Biosimilars are replacing originator compounds due to their similar effectiveness, safety and pharmacokinetics. Our objective was to compare the differences in pharmacokinetics and clinical outcomes between the originator infliximab (Ifx) and the biosimilar CT-P13 in a patient cohort with inflammato...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Martínez-Feito, Ana, Bravo-Gallego, Luz Yadira, Hernández-Breijo, Borja, Diez, Jesús, García-Ramirez, Laura, Jaquotot, Marta, Plasencia-Rodríguez, Chamaida, Nozal, Pilar, Mezcua, Araceli, Martín- Arranz, María Dolores, Pascual-Salcedo, Dora
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555902/
https://ncbi.nlm.nih.gov/pubmed/33051546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74235-1
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