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Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation

The differences in transcription start sites (TSS) and transcription end sites (TES) among gene isoforms can affect the stability, localization, and translation efficiency of mRNA. Gene isoforms allow a single gene diverse functions across different cell types, and isoform dynamics allow different f...

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發表在:Nat Commun
Main Authors: Hu, Youjin, Zhong, Jiawei, Xiao, Yuhua, Xing, Zheng, Sheu, Katherine, Fan, Shuxin, An, Qin, Qiu, Yuanhui, Zheng, Yingfeng, Liu, Xialin, Fan, Guoping, Liu, Yizhi
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555861/
https://ncbi.nlm.nih.gov/pubmed/33051455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18976-7
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