Longitudinal monitoring of circulating tumour DNA improves prognostication and relapse detection in gastroesophageal adenocarcinoma

BACKGROUND: Gastroesophageal adenocarcinoma (GOA) has poor clinical outcomes and lacks reliable blood markers. Here we present circulating tumour DNA (ctDNA) as an emerging biomarker. METHODS: Forty patients (17 palliative and 23 curative) were followed by serial plasma monitoring. Primary tumour DN...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Openshaw, Mark R., Suwaidan, Ali Abdulnabi, Ottolini, Barbara, Fernandez-Garcia, Daniel, Richards, Cathy J., Page, Karen, Guttery, David S., Thomas, Anne L., Shaw, Jacqui A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555811/
https://ncbi.nlm.nih.gov/pubmed/32719550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-1002-8
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