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Pathogenic Mechanisms of Myeloma Bone Disease and Possible Roles for NRF2

Osteolytic bone lesions are one of the central features of multiple myeloma (MM) and lead to bone pain, fractures, decreased quality of life, and decreased survival. Dysfunction of the osteoclast (OC)/osteoblast (OB) axis plays a key role in the development of myeloma-associated osteolytic lesions....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yen, Chia-Hung, Hsu, Chin-Mu, Hsiao, Samuel Yien, Hsiao, Hui-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555756/
https://ncbi.nlm.nih.gov/pubmed/32937821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186723
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