Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes

Multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are α-synucleinopathies that exhibit widespread astrogliosis as a component of the neuroinflammatory response. Munc18, a protein critical to vesicle exocytosis, was previously found to strongly mark morphologically activated astrocyte...

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Detalhes bibliográficos
Publicado no:Life (Basel)
Main Authors: Di Marco Vieira, Bruno, Radford, Rowan A. W., Hayashi, Junna, Eaton, Emma D., Greenaway, Ben, Jambas, Mark, Petcu, Eugen B., Chung, Roger S., Pountney, Dean L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555668/
https://ncbi.nlm.nih.gov/pubmed/32911644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10090183
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