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Cancer risks associated with the germline MITF(E318K) variant

The MITF(E318K) variant confers moderate risk for cutaneous melanoma. While there are small studies suggesting that this risk is associated with other malignancies (e.g. renal cell carcinoma), little is known about the role of this variant in specifying risk for other cancers. In this study, we perf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guhan, Samantha M., Artomov, Mykyta, McCormick, Shelley, Njauw, Ching -Ni, Stratigos, Alexander J., Shannon, Kristen, Ellisen, Leif W., Tsao, Hensin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555480/
https://ncbi.nlm.nih.gov/pubmed/33051548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74237-z
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