PARP Inhibitors in Biliary Tract Cancer: A New Kid on the Block?

Poly adenosine diphosphate-ribose polymerase inhibitors (PARPi) represent an effective therapeutic strategy for cancer patients harboring germline and somatic aberrations in DNA damage repair (DDR) genes. BRCA1/2 mutations occur at 1–7% across biliary tract cancers (BTCs), but a broader spectrum of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Medicines (Basel)
Päätekijät: Ricci, Angela Dalia, Rizzo, Alessandro, Bonucci, Chiara, Tober, Nastassja, Palloni, Andrea, Mollica, Veronica, Maggio, Ilaria, Deserti, Marzia, Tavolari, Simona, Brandi, Giovanni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555445/
https://ncbi.nlm.nih.gov/pubmed/32878011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines7090054
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