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Consensus-Based Pharmacophore Mapping for New Set of N-(disubstituted-phenyl)-3-hydroxyl-naphthalene-2-carboxamides

A series of twenty-two novel N-(disubstituted-phenyl)-3-hydroxynaphthalene- 2-carboxamide derivatives was synthesized and characterized as potential antimicrobial agents. N-[3,5-bis(trifluoromethyl)phenyl]- and N-[2-chloro-5-(trifluoromethyl)phenyl]-3-hydroxy- naphthalene-2-carboxamide showed submic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bak, Andrzej, Kos, Jiri, Michnova, Hana, Gonec, Tomas, Pospisilova, Sarka, Kozik, Violetta, Cizek, Alois, Smolinski, Adam, Jampilek, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555178/
https://ncbi.nlm.nih.gov/pubmed/32916824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186583
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