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4-Hydroxynonenal Immunoreactivity Is Increased in the Frontal Cortex of 5XFAD Transgenic Mice

Oxidative stress was implicated in the functional impairment of the frontal cortex observed in early Alzheimer’s disease (AD). To elucidate this role in an animal AD model, we assessed cognitive function of 4-month-old five familial AD (5XFAD) transgenic (Tg) mice using a learning strategy-switching...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Shin, Sang-Wook, Kim, Dong-Hee, Jeon, Won Kyung, Han, Jung-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554765/
https://ncbi.nlm.nih.gov/pubmed/32899155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8090326
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