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Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank

Laboratory studies have suggested oncogenic roles of lipids, as well as anticarcinogenic effects of statins. Here we assess the potential effect of statin therapy on cancer risk using evidence from human genetics. We obtained associations of lipid-related genetic variants with the risk of overall an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Carter, Paul, Vithayathil, Mathew, Kar, Siddhartha, Potluri, Rahul, Mason, Amy M, Larsson, Susanna C, Burgess, Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553780/
https://ncbi.nlm.nih.gov/pubmed/33046214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57191
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