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Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank

Laboratory studies have suggested oncogenic roles of lipids, as well as anticarcinogenic effects of statins. Here we assess the potential effect of statin therapy on cancer risk using evidence from human genetics. We obtained associations of lipid-related genetic variants with the risk of overall an...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Carter, Paul, Vithayathil, Mathew, Kar, Siddhartha, Potluri, Rahul, Mason, Amy M, Larsson, Susanna C, Burgess, Stephen
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553780/
https://ncbi.nlm.nih.gov/pubmed/33046214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57191
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