Ablation of C3 modulates macrophage reactivity in the outer retina during photo-oxidative damage

PURPOSE: Dysregulation of the complement cascade contributes to a variety of retinal dystrophies, including age-related macular degeneration (AMD). The central component of complement, C3, is expressed in abundance by macrophages in the outer retina, and its ablation suppresses photoreceptor death i...

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Опубликовано в: :Mol Vis
Главные авторы: Jiao, Haihan, Provis, Jan M., Natoli, Riccardo, Rutar, Matt
Формат: Artigo
Язык:Inglês
Опубликовано: Molecular Vision 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553722/
https://ncbi.nlm.nih.gov/pubmed/33088172
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