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Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils
Fibrillar aggregates of amyloid-β (Aβ) are the main component of plaques lining the cerebrovasculature in cerebral amyloid angiopathy. As the predominant Aβ isoform in vascular deposits, Aβ(40) is a valuable target in cerebral amyloid angiopathy research. However, the slow process of Aβ(40) aggregat...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7553346/ https://ncbi.nlm.nih.gov/pubmed/33048999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240608 |
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