Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms

People with HIV (PWH) are at increased risk for atherosclerotic cardiovascular disease (ASCVD). Proportions of vascular homing monocytes are enriched in PWH; however, little is known regarding monocyte-derived macrophages (MDMs) that may drive atherosclerosis in this population. We isolated PBMCs fr...

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Publicado en:PLoS Pathog
Main Authors: Bowman, Emily R., Cameron, Cheryl M., Richardson, Brian, Kulkarni, Manjusha, Gabriel, Janelle, Cichon, Morgan J., Riedl, Kenneth M., Mustafa, Yousef, Cartwright, Michael, Snyder, Brandon, Raman, Subha V., Zidar, David A., Koletar, Susan L., Playford, Martin P., Mehta, Nehal N., Sieg, Scott F., Freeman, Michael L., Lederman, Michael M., Cameron, Mark J., Funderburg, Nicholas T.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553323/
https://ncbi.nlm.nih.gov/pubmed/33002093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008869
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